EVALUATION OF PHYTOCHEMICAL AND PHARMACOLOGICAL SCREENING OF AMOMUM SUBULATUM, ELETTARIA CARDAMOMUM AND MOMORDICA CHIRANTIA AND THEIR COMBINATION
Khushi Thapar, Khushi Patel, Keshav Chandra, Kuldeep Bhade, Rakesh Gawaly
ABSTRACT
This study investigates the phytochemical composition and in vitro antidiabetic activity of ethanolic extracts of Amomum subulatum, Elettaria cardamomum, and Momordica charantia, along with their combination. The percentage yield of each extract was recorded, and phytochemical screening revealed the presence of various bioactive constituents, including alkaloids, flavonoids, phenolics, saponins, and proteins. In vitro ?-amylase inhibition assays were performed to assess antidiabetic potential. Among the individual extracts, Momordica charantia showed the highest inhibitory activity. Notably, the combination of all three extracts in a 1:1:1 ratio demonstrated significantly enhanced ?-amylase inhibition, indicating a synergistic effect. These results support the potential use of these plants, individually and in combination, as natural antidiabetic agents. Further in vivo studies and pharmacological evaluations are needed to confirm their therapeutic applicability.
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