PREPARATION AND EVALUATION OF HERBAL MOUTHWASH CONTAINING METHANOLIC EXTRACT OF WITHANIA SOMNIFERA ROOT
Priyansh Patel, Deepak Kumar Basedia, B. K. Dubey
ABSTRACT
This study focuses on the preparation and evaluation of a herbal mouthwash containing methanolic extract of Withania somnifera (Ashwagandha) root, aiming to assess its potential as a natural alternative for oral hygiene. The methanolic extract was obtained with a yield of 11.6%, and preliminary phytochemical screening revealed the presence of alkaloids, glycosides, phenols, carbohydrates, flavonoids, and proteins. The mouthwash, formulated with this extract, exhibited desirable characteristics including a pH of 6.2 and foaming ability. Antibacterial testing showed significant antimicrobial activity, particularly against Streptococcus mutans and Klebsiella pneumoniae, with higher concentrations of the extract producing larger zones of inhibition. These results suggest that the herbal mouthwash has potential antibacterial and therapeutic properties, making it a promising natural product for oral care, with the added benefit of being gentle on oral tissues.
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