STUDY OF PHYTOCHEMICALS AND ANTIACNE ACTIVITY OF ETHANOLIC BARK EXTRACT OF ZANTHOXYLUM ARMATUM
Pratiksha Banwale, Surendra Jain
ABSTRACT
The ethanolic extract of Zanthoxylum armatum, a plant native to various regions of Asia, has emerged as a potential candidate for acne treatment due to its rich content of bioactive compounds. This study aimed to evaluate the phytochemical profile and anti-acne activity of the ethanolic extract of Zanthoxylum armatum. Phytochemical analysis revealed the presence of carbohydrates, flavonoids, phenols, saponins, proteins, and alkaloids, which are known for their antimicrobial and anti-inflammatory properties. The anti-acne activity of the extract was assessed against Propionibacterium acnes and, although less potent than Clindamycin, demonstrated significant antibacterial effects at higher concentrations. These findings suggest that the ethanolic extract of Zanthoxylum armatum could serve as a natural alternative or adjunct treatment for acne, leveraging its anti-inflammatory, antioxidant, and antimicrobial actions. Future studies should focus on enhancing the efficacy of the extract, understanding its specific mechanisms of action, and exploring its potential in clinical applications.
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