EXTRACTION, PHYTOCHEMICAL SCREENING AND ANTIPYRETIC ACTIVITY OF BALANITES AEGYPTIACA
Pooja Singh, Surendra Kumar Jain, K.K Badoniya
ABSTRACT
This study aimed to explore the potential antipyretic activity of Balanites aegyptiaca through extraction, phytochemical screening, and evaluation of its biological properties. The methanolic extract of Balanites aegyptiaca exhibited a yield of 7.6% w/w and was subjected to phytochemical analysis, revealing the presence of carbohydrates, saponins, phenols, and alkaloids, while proteins, diterpenes, glycosides, flavonoids, tannins, and specific alkaloids were absent. Quantitative analysis showed the extract contained 0.35 mg/100 mg of total phenols and 0.72 mg/100 mg of total flavonoids. To assess its antipyretic potential, the extract was tested using a yeast-induced pyrexia model in rats. The results demonstrated that administration of the extract significantly reduced rectal temperatures compared to the control group over a 3-hour period. Group III, treated with the extract, showed notable temperature reduction, suggesting effective antipyretic activity. These findings highlight Balanites aegyptiaca as a potential source of antipyretic agents, likely mediated through its antioxidant constituents. Further research is warranted to elucidate the underlying mechanisms and to explore clinical applications for managing fever-related conditions.
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