POLYHERBAL FORMULATION USED IN ARTHRITIS
Ajay Yadav, Arpit Shrivastav, Harshita Jain, Neeraj Bansal, Amit Vishwas, Vaishali Yadav
ABSTRACT
Arthritis, a prevalent inflammatory joint disorder, presents significant challenges in management, often leading to the exploration of alternative therapies. This study investigates the extraction efficiency and phytochemical profiles of Nyctanthes arbor-tristis (night-flowering jasmine) and Azadirachta indica (neem), both recognized for their therapeutic potential in inflammatory conditions. A series of extraction processes were conducted to obtain petroleum ether and aqueous extracts, followed by phytochemical screening to identify bioactive compounds. Results indicated varying yields and a distinct presence of flavonoids, tannins, and saponins in the extracts. A polyherbal formulation combining both extracts was developed and characterized for its physical properties, viscosity, extrudability, and skin compatibility. Preliminary efficacy tests demonstrated promising effects on inflammatory markers in an animal model of arthritis. These findings support the potential of a polyherbal approach in arthritis management, highlighting the need for further investigations into the synergistic effects of these herbal constituents.
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