PHYTOCHEMICAL SCREENING AND ANTIDIABETIC ACTIVITY OF DELONIX REGIA PLANT
Darshana Rohitas, Harshita Jain, Vaishali Yadav, Arpit Shrivastava, Sunil Kumar Jain
ABSTRACT
The study investigates the antidiabetic potential of the ethanolic extract of Delonix regia through both phytochemical analysis and in vivo experiments in diabetic rats. Phytochemical tests revealed the presence of key bioactive compounds, including carbohydrates, flavonoids, phenols, proteins, diterpenes, and tannins. Quantitative estimation showed that the extract contains 0.752 mg/100 mg of flavonoids and 0.433 mg/100 mg of phenols. Diabetic rats treated with the extract exhibited a significant reduction in blood glucose levels, with the group receiving 200 mg/kg/day showing a decrease from 267.00±2.70 mg/dL to 130.00±1.80 mg/dL over 30 days. The extract also improved lipid profiles, reducing total cholesterol and triglycerides, and positively influenced serum insulin levels and glycosylated hemoglobin. These findings suggest that Delonix regia has promising antidiabetic properties, likely due to its rich phytochemical composition. However, further research, including human clinical trials, is necessary to fully elucidate its therapeutic potential and safety.
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