International Journal of Pharmaceutics & Drug Research

Nand Kumar Dubey, Anshita Gupta, Dr. Vivek Gupta

ABSTRACT

This study focuses on the formulation and evaluation of a novel silver nanoparticle gel incorporating the hydroalcoholic extract derived from Scaphium affine fruits. The aim is to harness the antimicrobial potential of Scaphium affine, a plant renowned for its medicinal properties. The silver nanoparticle gel was meticulously formulated using hydroalcoholic extraction and nanoprecipitation techniques, and its physicochemical characteristics were comprehensively assessed. The antimicrobial efficacy was evaluated against a spectrum of pathogenic microorganisms, elucidating the potential of the developed gel as an antimicrobial agent. The results indicate successful synthesis of silver nanoparticles within the gel matrix, characterized by advanced analytical techniques. Furthermore, the gel demonstrated significant antimicrobial activity, showcasing its potential application in the development of pharmaceutical and cosmetic formulations with enhanced therapeutic benefits. This research contributes to the growing body of knowledge on plant-based antimicrobial agents and opens avenues for the utilization of Scaphium affine in the field of nanomedicine. The silver nanoparticle gel emerges as a promising candidate for further studies and potential applications in the realm of infectious disease management and skincare formulations.

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