ADVANCEMENTS OF ORODISPERSIBLE TABLETS: A COMPREHENSIVE REVIEW
Chaitali Vinod Kannamwar, Dr. Pankaj M. Pimpalshende, Dr. Satish B. Kosalge
ABSTRACT
Orodispersible tablets (ODTs) have become a popular and accommodating dose form that solves problems with traditional tablets and offers creative ways to distribute medications. This thorough analysis examines the most recent developments in ODTs, emphasizing their history, characterization methods, formulation strategies, applications, difficulties, and potential applications. The assessment of ODTs in comparison to traditional tablets is covered, emphasizing the special qualities that make them appropriate for a range of patient demographics. To clarify their effects on ODT disintegration and drug release, formulation techniques such as direct compression, sublimation, and the function of superdisintegrants are investigated. In order to guarantee product quality, analytical methods for characterizing ODTs such as disintegration time, hardness, and drug content uniformity are severely assessed. The review explores the diverse therapeutic areas in which ODTs can be applied, with a focus on emergency medicine, psychiatry, pediatrics, and geriatrics. Taste masking, stability, and scalability challenges are explored, offering insights into future research directions and possible breakthroughs, such as 3D printing and nanotechnology. Conclusively, this thorough study provides a great resource for researchers, pharmaceutical professionals, and clinicians who wish to gain a deeper understanding of this novel drug delivery platform by consolidating current knowledge on ODTs.
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