EVALUATION OF ANTI INFLAMMATORY ACTIVITY OF STERCULIA LYCHNOPHORA FRUITS
Mohd. Noman Waheed, Dr. Satkar Prasad
ABSTRACT
The extensive activity of study on herbal plant species and their medicinal principles across the entire world is used to evaluate Indian herbal medicine. Medicinal plants that have demonstrated their potential in possessing powerful bioactive compounds are employed in both traditional and modern medicine. A vast number of people suffer from rheumatoid arthritis of unknown inflammation for a variety of reasons. Thus, this study deals with evaluation of anti -inflammatory activity of Sterculia lychnophora fruits. The fruits of the plant was collected, extracted, subjected to qualitative & quantitative tests. Further the in vivo anti -inflammatory activity was checked in carrageen induced paw edema model. Results showed that the phytochemical tests revealed the presence of alkaloid, glycoside, tannin, flavonoid, steroid, & Phenol. The total phenol & flavonoid content was found to be 0.857 mg/100mg & 0.922 mg/100mg respectively. The paw edema was found to be 2.75±0.32 & 1.23±0.20 at the end of 4 hrs in 100 mg/kg & 200 mg/mg respectively. In case of standard drug indomethacin the paw edema volume at end of 4th hour was noted as 1.05±0.15. Thus it can be concluded that the extract has anti-inflammatory potential nearly equal to that of standard drug.
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