FORMULATION AND EVALUATION OF PHYTOSOMES FOR ENHANCEMENT OF BIOAVAILABILITY OF ETHANOLIC EXTRACT OF PISTACIA LENTISCUS L.
Ankita Pal, Diksha Bundela, Pratyush Jain, Nishi Prakash Jain
ABSTRACT
This study explores the formulation and evaluation of phytosomes as a novel strategy to enhance the bioavailability of the ethanolic extract of Pistacia lentiscus L., a plant renowned for its therapeutic potential. Phytosomes, complex structures formed by combining natural phospholipids with bioactive compounds, offer an innovative solution to address the limited bioavailability of the plant extract. Characterization, in vitro release studies, and pharmacokinetic assessments were conducted to evaluate the effectiveness of the phytosomal formulation. The results indicate a significant improvement in bioavailability, suggesting the clinical relevance of this approach. Safety and tolerability assessments further support the potential utility of phytosomes for enhancing the therapeutic applications of Pistacia lentiscus L. extract
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