PHARMACOLOGICAL EVALUATION FOR THE ETHANOLIC EXTRACT OF EVOLVULUS ALSINODES RHIZOME FOR IT’S ANTI - ASTHMATIC, ANTIOXIDANT AND ANTI – INFLAMMATORY ACTIVITIES
Dhruv Kumar Yadav, Bablu Kumar Gupta, Shruti Mittal, Prashant Gupta*
ABSTRACT
Asthma is a chronic inflammatory lung disease that can cause repeated episodes of cough, wheezing and breathing difficulty. During an acute asthma episode, the airway lining in the lungs becomes inflamed and swollen. In addition, mucus production occurs in the airway and muscles surrounding the airway spasm. Combined, these cause a reduction in air flow. 1 Overall, free radicals have been implicated in the pathogenesis of at least 50 diseases. Fortunately, free radical formation is controlled naturally by various beneficial compounds known as antioxidants. It is when the availability of antioxidants is limited that this damage can become cumulative and debilitating. In recent year there has been tremendous increase in demand for herbal drugs because of its safety, efficacy and better therapeutic results. Due to its economic pricing as compared to synthetic or allopathic drugs, which have several therapeutic compilations. Evolvulus Alsinodes is also considered to be therapeutically important in traditional system of medicine. Aim of the study to evaluate the anti-asthmatic, antioxidant and anti-inflammatory activities of ethanolic extract of Evolvulus Alsinodes rhizome
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