ASSESSMENT OF HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITY OF SALVADORA PERSICA L. AGAINST ALACTOSAMINE INDUCE OXIDATIVE STRESS IN RATS
Bablu Kumar Gupta, Dhruv Kumar Yadav, Shruti Mittal, Prashant Gupta
ABSTRACT
Two essential changes bring about irreversible cell injury in necrosis is cell digestion by lytic enzymes and denaturation of proteins. These processes are morphologically identified by characteristic cytoplasmic and nuclear changes in necrotic cell. The cytoplasm appears homogeneous and intensely eosinophilic. Occasionally, it may show vacuolation or dystrophic calcification. Hepatotoxicity can affect hundreds of millions of people worldwide. It is the common nonneo plastic cause of death among hepatobiliary and digestive disorders serious side effects, the cost of the modern medicine and improper channel of treatment and competitive efficacy of natural products made the person through the world to look for classical plant drugs for the treatment of hepatotoxicity. In view of the pharmacological and biological properties and chemical constituents of the plant Salvadora Persica, it was decided to an attempt is made to find out the extent of hepatoprotective and antioxidant activity of plant.
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