FORMULATION AND CHARACTERIZATION OF BLEND MICROSPHERES OF ANTIDIABETIC DRUG
Rahul Singh*, Abhishek Kumar Sen, Dr. Kavita R. Loksh, Dr. Sarita Karole
ABSTRACT
The formulation and characterization of blend microspheres encapsulating the antidiabetic drug glimepiride represent a significant advancement in drug delivery systems for diabetes management. Blend microspheres were developed to improve the therapeutic efficacy of glimepiride while minimizing side effects and enhancing patient compliance. This study encompasses the efficient formulation of microspheres using biocompatible polymers, detailed characterization of their properties, and the evaluation of drug release profiles. Key findings include sustained drug release, enhanced bioavailability, reduced side effects, and improved patient compliance. The stability and compatibility of glimepiride within the microspheres were also investigated. This research offers valuable insights into the potential of blend microspheres as a novel approach to optimize glimepiride therapy in diabetes treatment.
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