MANAGEMENT OF HYPERGLYCEMIC OF METHANOLIC ROOT EXTRACT OF LIPPA NODIFLORA
Shivani Khatri, Pawan Bajpai*
ABSTRACT
Diabetes mellitus is a group of syndromes characterized by hyperglycemia, altered metabolism of lipids, carbohydrates and proteins, and an increased risk of complications from vascular disease. More than 400 species of plants have been reported to display hypoglycemic effects, but only a few of them have been investigated. Although many drugs are available to control the diabetes but has several adverse effects. Lippa nodiflora highly reputed plant in ayurvedic system of medicine for the treatment of various ailments. The plant was reported to have activities such as purgative, antiasthmatic, antihelmintic, used in the treatment of headaches, antioxidant and anti-diabetic. This study was undertaken to investigate the anti-diabetic activity of extract of stem bark of Lippa nodiflora in alloxan induced diabetic rats. The present study is undertaken to standardize the Lippa nodiflora and to evaluate its anti-diabetic activity with emphasize to its mechanism of action. The validation of anti-diabetic property is correlated with various biochemical parameters involved therein.
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