FORMULATION AND CHARACTERIZATION OF ORODISPERSIBLE FILMS OF SOLANUM XANTHOCARPUM
Roop Singh Lodhi1, Dr. Vivekanand Katare*1, Mrs. Abhilasha Delouri1, Mr. Prabhat Kumar Jain 2
ABSTRACT
Solanum xanthocarpum belongs to the family Solanaceae commonly known as the Indian night shade or Yellow berried night shade (English) and kantakari (Sanskrit). Solanum xanthocarpum has played an important role in the traditional medicine. The aim of present invention is to formulate and develop ODFs of hydro-alcoholic extract of Solanum xanthocarpum. ODFs of Solanum xanthocarpum extract were prepared using solvent casting method. The percentage yield of Hydroalcoholic extract of Solanum xanthocarpum was found to 3.35 % by using maceration method under laboratory conditions. The results of phytochemical screening show the presences of various bioactive compounds such as Carbohydrates, Flavonoids, Proteins & Amino acids, Diterpenes and Saponins. Phenol s or phenolic compounds were found to absent in Hydroalcoholic extract Solanum xanthocarpum roots. Among the prepared formulations, formulation F1 was found to have transparent visual appearance, best film forming capacity, least disintegration time and also found to be stable at accelerated stability studies. Evaluation of the films confirmed their potential as an innovative dosage form to deliver Solanum xanthocarpum.
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