PHYTOCHEMICAL SCREENING AND IN-VITRO ANTIDIABETIC STUDIES OF METHANOLIC EXTRACTS OF CASSIA TORA
Pooja Uikey1, Dr. Vivekanand Katare*1, Mrs. Abhilasha Delouri1, Mr. Prabhat Kumar Jain 2
ABSTRACT
In this study, medicinal plants, namely Cassia tora (Family - Caesalpiniaceae) was studied for phytochemical screening and possible effects on starch breakdown by ?-amylase in vitro. The percentage yield of plant was calculated as per standard method. The yields were found to be 4.2 g (8.4% w/w of crude drug) of Methanolic extract. Total Flavonoid content was determined quercetin equivalent in MECT. Acarbose (at a concentrations 100 ?g/mL) showed 58.31% inhibitory effects on the ?-amylase activity with an IC50 value 84.19±021 ?g/mL. The methanol extracts of Cassia tora (at a concentration 100 ?g/mL) exhibited 75.31% of ?-amylase inhibitory activity with an IC50 values 57.19±014 ?g/mL. The results of study indicate that methanolic extract of Cassia tora plant showed appreciable ?-amylase inhibitory effects.
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