IJPDR

International Journal of Pharmaceutics & Drug Research

ISSN No. 2347-6346

Abstract

PHYTOCHEMICAL SCREENING AND IN-VITRO ANTIMICROBIAL ACTIVITY OF HYDROALCOHOLIC EXTRACT OF STEM OF BAUHINIA VARIEGATE

Dr. Peenu Mahendra Joshi*, Dr. Jaswinder Mehta, Naresh Kumar, Aaradhana Vishwakarma,
Dr. Bhawna Sharma, Dr.Ruchi Acharya

ABSTRACT

Infectious diseases are the second leading cause for worldwide death. Treatment of infections continues to be difficult in modern time because of the severe side effects of some drugs and the growing resistance to antibacterial agents. Over the past few decades the use of antibiotics is under threat as many commonly used antibiotics have become less effective against certain illnesses due to emergence of multi drugresistant bacteria. Bauhinia variegate showed the presence of flavonoid, diterpenes, proteins, carbohydrate, saponins while, Alkaloids, Glycosides and Phenol were not detected. The total flavonoids estimation of stem hydroalcoholic extract of Bauhinia variegate showed the content values of 5.062 mg/100 mg respectively. Results of antimicrobial activity of the plant extract were found more effective against Klebsiella pneumoniae followed by Staphylococcus aureus. Phytochemicals present in extracts showed antimicrobial activities. MIC value shows that plant extracts have antimicrobial activity against Klebsiella pneumonia and Staphylococcus aureus.

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