EVALUATE BIOACTIVE CONSTITUENTS AND ANTIPYRETIC POTENTIAL OF HYDROALCOHOLIC EXTRACTS OF FOENICULUM VULGARE
Rahul Verma*, C. K. Tyagi, Prabhakar Budholiya
ABSTRACT
Medicinal plants are assuming greater importance in the primary health care of individuals and communities in many developing countries. Indian medicinal plants and their derivatives have been an invaluable source of therapeutic agents to treat various disorders. Herbal products are often perceived as safe because they are “natural”. Foeniculum vulgare Mill. (Apiaceae family) commonly-known as fennel, is one of the widespread annual or perennial plants with an aromatic odor. Foeniculum vulgare (Apiaceae) is a popular plant with valuable medicinal and culinary importance. It is mostly used in the treatment of ailments associated with digestive and respiratory systems, so our aim of the study is extraction, phytochemical screening and anti- antipyretic activity of Foeniculum vulgare seeds extract. The Antipyretic effect of Hydroalcoholic extract of seeds of Foeniculum vulgare significantly lowered the temperature in yeast induced pyrexia. The lowering of temperature was almost in a similar manner to that of reference drug, paracetamol, suggesting that the plant have antipyretic property which can be assumed to be mediated through interference of prostaglandin synthesis and inhibition of cytokines release. The conclusion of the study demonstrated that Hydroalcoholic extract of leaves of Foeniculum vulgare displayed antipyretic property.
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